If anything, your car is going to want to tramline and become more sensitive with toe at 0 up front.
For me, I have 0 toe up front and the car usually wants to drift right, as the crown of the road is sloped that way. Any rut though and the tires will quickly follow that direction.
Toe-in will reduce feel on your front tires and induce understeer quicker than 0 toe.
As for the rear, toe-in essentially fights forward motion, so it isn't crazy to think that MPG has gone down as a result. I haven't experienced the same though when I went from 1/8" total to 1/4" total toe in on the rear tires.
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